There are derby matches to be played at Stradey, where Llanelli entertain Aberavon and the Gnoll, where Neath take on Swansea.
Also in the Premier division are all-Gwent battles between Bedwas-Pontypool and Newport-Cross Keys, while Newbridge travel to Pontypridd and Ebbw Vale will recall several hard matches over the last few seasons as they take on Caerphilly, though Bridgend are visitors at Llandovery for the first time in league rugby.
Premier Division 27/09/03
Bedwas v Pontypool
Carmarthen Qns v Cardiff
Ebbw Vale v Caerphilly
Llandovery v Bridgend
Llanelli v Aberavon
Neath v Swansea
Newport v Cross Keys
Pontypridd v Newbridge
