Gorseinon took a chance last week with league and cup games, eventually defeating Trimsaran in the West Division, but going out of the cup.
They take their unbeaten league record to Aberystwyth, who also have not dropped a point. Both Loughor and Pembroke Dock Quins have also 100% records.
In the South-East, top dogs Mountain Ash go to Penygraig in the hope that the home side will field this week, while Rhydyfelin entertain Tonyrefail and Pentyrch face the might of Gilfach Goch.
The three unbeaten clubs of the South-West, Vardre, Bryncoch and Skewen all have home games, against Kenfig Hill, Nantyffyllon and Aberavon Quins respectively.