Ystrad Rhondda will host Merthyr while Beddau will travel to Bonymaen. In the other two games Penallta are at home to Bridgend Athletic whil Tondu visit Glamorgan Wanderers.
The matches are to be played over the weekend of 12th-14th February, the weekend of the Wales v Scotland match.
Third Round
Ystrad Rhondda v Merthyr
Bonymaen v Beddau
Penallta v Bridgend Athletic
Glamorgan Wanderers v Tondu
Second Round Results
Ystrad Rhondda 15 Abercrave 3
Bonymaen 18 Hendy 16
Beddau 6 Whitland 3
Bridgend Athletic 55 Ystradgynlais 0
Penallta 27 Neath Athletic 10
Ammanford 6 Tondu 27
Crymych 3 Merthyr 11
Newport HSOB 0 Glamorgan Wanderers 54