No. 8 and captain Andries Pretorius has been forced to pull out of the match with the Irish province after failing to recover from a rib injury sustained in last week’s defeat to Leinster.
Phil Davies’ side will be looking to bounce back from a disappointing display in Dublin though they will have to do so without Pretorius.
Robin Copeland moves from flanker to No. 8 while young back-row forward Luke Hamilton is promoted from the bench to start at blindside.
Thomas Young takes Hamilton’s place on the bench.