Nicky Roberts, Jimmy Norris and Daniel Preece are set to make their full debuts while Craig Morgan and Richard Jones form a new midfield partnership and Darren Allinson starts at scrum-half.
Adam Powell, Jake Thomas and Matthew Veater return to the pack where Garry Horrigan also makes his first start of the campaign and Jamie Ringer leads the side for the first time.
Cardiff: Nicky Roberts; Ryan Howells, Craig Morgan, Richard Jones, Jimmy Norris; Gareth Davies, Darren Allinson; Daniel Preece, Garry Horrigan, Phil Osborne, Matthew Veater, Ashley Sweet, , Jamie Ringer (captain), Adam Powell, Jake Thomas Replacements: Leighton Davies, Ian George, Dan Partridge, Daniel Godfrey, Garyn Lucas, Owen Williams, Gareth Chapman
