Cardiff have the problem of playing at the Arms Park less than 24 hours after the Blues have met Stade Francais as they come up against Pontypool, while Aberavon hope two weeks without a match will end as they take on Pontypridd at the Talbot Athletic Ground.
While Llanharan are the bye team, Carmarthen Quins hope to return to winning ways against a Bedwas side who do travel well. Bottom club Caerphilly face up to Ebbw Vale at Virginia Park and Swansea meet Newbridge at St Helen’s.