In the West, the big clash is at Neyland, where Cefneithin are the visitors. If there is not a draw, the winners will join Amman Utd on 18 points. In the other matches, Fishguard take on Milford Haven and Pontarddulais meet Betws.
The only match in the South-East is at Dowlais, where Llandaff North provide the opposition and in the South-West leaders Resolven visit bottom club Pyle, while Aberavon Green Stars meet Glais; Trebanos take on Maesteg Celtic and Ystradgynlais face Morriston.